| Heim | Resultat | Gast | Stadion |
| Sevilla F. C. | 0 – 0 | Levante U. D. | Sánchez Pizjuán |
| Athletic Club | 0 – 0 | Real Sociedad | San Mamés |
| S. D. Eibar | 2 – 1 | Valencia C. F. | Ipurúa |
| Atlético de Madrid | 1 – 0 | Deportivo Alavés | Wanda Metropolitano |
| Girona F. C. | 1 – 0 | Getafe C. F. | Montilivi |
| R. C. Celta de Vigo | 0 – 1 | Villarreal C. F. | Balaídos |
| U. D. Las Palmas | 2 – 2 | R. C. D. Español | Gran Canaria |
| F. C. Barcelona | 4 – 0 | R. C. Deportivo de La Coruña | Camp Nou |
| Málaga C. F. | 0 – 2 | Real Betis | La Rosaleda |
| C. D. Leganés | 1 – 3 | Real Madrid C. F. | Butarque |
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Spain_location_map.svg: NordNordWestderivative work: Ottobdn (talk) - Spain_location_map.svg, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=15371900